Australia’s National immunisation surveillance system, AusVaxSafety, is giving Australians insight into how they might react to a COVID-19 vaccine. Overall, 51.5% of Australian responders reported no side effects after their vaccination, with 48.5% experiencing at least one side effect. The most common side effects have been pain at the injection site, fatigue and headaches. However, only 1.2% had bad enough side effects to visit a doctor or hospital.