AirSense 10 vs AirSense 11: Which CPAP Machine to Choose? March 20, 2025 Since its debut in 2014, the ResMed AirSense 10 AutoSet has been the go-to CPAP machine for sleep apnea therapy. But now, ResMed has released the AirSense 11 AutoSet, a sleeker and smarter model designed to make therapy even more personalized. Let's compare their key differences. Design and Portability The AirSense 11 is lighter and more compact, making it easier to travel with. It weighs just 1130 g, compared to the AirSense 10’s 1428 g. It also has a 24% smaller footprint, saving bedside space. Ease of Use and Controls The AirSense 10 uses traditional knob-and-button controls, while the AirSense 11 features a modern touchscreen with adaptive brightness for easier navigation. Power and Efficiency The AirSense 11 operates on a more energy-efficient 65 W power supply, compared to the 90 W supply of the AirSense 10, while delivering the same therapy performance. Noise and Quietness Both models are among the quietest CPAP machines available. The AirSense 10 operates at 26.6 dB, while the AirSense 11 runs at 27 dB—an indistinguishable difference in real-world use. Humidification and Water Chamber Both machines feature built-in humidification. The AirSense 11’s redesigned water chamber has a wider base for easier handling and refilling, though the capacity remains the same. The chambers are not interchangeable. Set-Up Features and Software The AirSense 11 includes smart features like Test Drive, Personal Therapy Assistant, Care Check-In, and automatic software updates, all aimed at improving user experience. The AirSense 10 lacks these but still provides reliable therapy with essential options like Ramp, EPR, and Auto Start/Stop. Comparison Table Feature AirSense 10 AutoSet AirSense 11 AutoSet Weight 1428 g 1130 g AutoRamp with sleep onset detection ✔ ✔ SmartStart/Stop feature ✔ ✔ Test Drive Not included ✔ Personal Therapy Assistant Not included ✔ Care Check-In Not included ✔ OTA Software Updates Not included ✔ myAir App Compatibility ✔ ✔ Supplemental Oxygen Use Up to 4L/min Up to 15L/min AutoSet for Her Algorithm Not included ✔ Bluetooth Connectivity Not included ✔ Built-in Cellular Technology ✔ ✔ Humidification (Fully Integrated) ✔ ✔ Final Thoughts If you already have an AirSense 10 and it’s working well for you, there’s no urgent need to upgrade. However, if you're looking for a lighter design, touchscreen controls, and advanced digital features, the AirSense 11 is a strong contender. For frequent travelers, the ResMed AirMini travel CPAP machine is also an option, featuring waterless humidification and a more compact design, though it lacks some of the comfort features of the full-sized models. Ultimately, the best CPAP machine for you depends on your needs, preferences, and budget. The most important factor is consistent usage for effective therapy. ALWAYS FOLLOW THE DIRECTIONS FOR USE. CPAP is used for Obstructive Sleep Apnea treatment. When considering whether CPAP is right for you, speak to your doctor.